Myriad
Genextest LLC is an official distributor of Myriad in Estonia and Russia.
Myriad offers an array of genetic tests, prognostic tests, and personalized medicine tests to healthcare providers to help them assess a patient’s increased cancer risk, disease aggressiveness, optimize efficacy of chemotherapy and identify patients’ most suitable for therapy.
BREAST CANCER
EndoPredict® is the only test that answers the following three important clinical questions…
- Can chemotherapy be avoided? (individual risk at 10 years)
- What is the absolute benefit from chemotherapy? (individual chemotherapy benefit)
- Can endocrine therapy be stopped after 5 years? (individual risk up to 15 years)
… to optimize treatment for breast cancer patients.
PROSTATE CANCER
Prolaris® is a molecular diagnostic test that measures the expression level of genes involved with tumor proliferation to predict disease outcome. Prolaris can be used in conjunction with other clinical parameters to determine prostate cancer aggressiveness.
HEREDITARY CANCER
Myriad myRisk® Hereditary Cancer is a 35-gene panel that helps to determine a patient’s risk by evaluating a number of hereditary cancer syndromes, with focus on eight primary cancer sites.
RiskScore® is a clinically validated algorithm that predicts a woman’s remaining 5-year and lifetime risk of developing breast cancer at no additional cost (as the additional option for MyRisk test).
The BRACAnalysis® test assesses a person’s risk of developing hereditary breast or ovarian cancer based on the detection of mutations in the BRCA1 and BRCA2 genes.
COLARIS® testing assesses a person’s risk of developing hereditary colorectal cancer and a woman’s risk of developing hereditary uterine/endometrial cancer by detecting disease-causing mutations in the MLH1, MSH2, MSH6 and PMS2 genes.
COLARIS AP® testing assesses a person’s risk of developing hereditary colorectal polyps and cancer by detecting mutations in the APC and MYH genes.
PRECISION MEDICINE
myChoice CDx is the first and only FDA-approved tumor test that determines homologous recombination deficiency status by detecting BRCA1 and BRCA2 (sequencing and large rearrangement) variants and assessing genomic instability using three critical biomarkers: loss of heterozygosity, telomeric allelic imbalance and large-scale state transitions.
myChoice CDx PLUS identifies patients that are most likely to benefit from PARP inhibitors. It is the only commercially available tumor test that has been designed to detect large rearrangements which account for 5% of all ovarian cancer mutations.
BRACAnalysis CDx® is an FDA-approved laboratory developed test for BRCA1 and BRCA2 intended to inform patient management related to the PARP inhibitors, Lynparza® (olaparib) and Zejula® (niraparib).
Melanoma
Myriad myPath® Melanoma is a clinically validated test to be used as an adjunct to histopathology when the distinction between a benign nevus and a malignant melanoma cannot be made confidently by histopathology alone.